{"id":84406,"date":"2024-09-05T11:26:04","date_gmt":"2024-09-05T11:26:04","guid":{"rendered":"https:\/\/pakistaninewspaperlist.com\/news\/biontech-to-present-clinical-data-updates-across-mrna-and-immunomodulatory-oncology-portfolio-at-esmo-congress-2024\/"},"modified":"2024-09-05T11:26:04","modified_gmt":"2024-09-05T11:26:04","slug":"biontech-to-present-clinical-data-updates-across-mrna-and-immunomodulatory-oncology-portfolio-at-esmo-congress-2024","status":"publish","type":"post","link":"https:\/\/pakistaninewspaperlist.com\/news\/biontech-to-present-clinical-data-updates-across-mrna-and-immunomodulatory-oncology-portfolio-at-esmo-congress-2024\/","title":{"rendered":"BioNTech to Present Clinical Data Updates Across mRNA and Immunomodulatory Oncology Portfolio at ESMO Congress 2024"},"content":{"rendered":"<div id=\"main-body-container\" itemprop=\"articleBody\">\n<p align=\"justify\"><strong>MAINZ, Germany, September 05, 2024 <\/strong>\u2013 <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=gpsZy7oaDr-iBARBx7Ypbpxs0AJbZhLvGlLtY0uA0YN5Ego4Qft_2D3KmSIRT62FmTc0Gf7abs867r5jckYmPFYUjpNn4AbsrC0HC9cjZZ0=\" rel=\"nofollow noopener\" target=\"_blank\" title=\"\"><u>BioNTech SE<\/u><\/a> (Nasdaq: BNTX, \u201cBioNTech\u201d or \u201cthe Company\u201d) will present clinical trial data for selected assets from its multi-platform oncology pipeline at the European Society for Molecular Oncology (\u201cESMO\u201d) Congress 2024 in Barcelona, Spain from September 13-17, 2024. The oral and poster presentations will feature programs across BioNTech\u2019s clinical pipeline, including mRNA-based cancer vaccines, next-generation immunomodulators and targeted therapy approaches.<\/p>\n<p align=\"justify\">\u201cWe believe that the future of cancer treatment will be driven by the combination of modalities, including immunomodulators, targeted and mRNA-based therapies,\u201d said <strong>Prof. \u00d6zlem T\u00fcreci, M.D., Co-Founder and Chief Medical Officer at BioNTech<\/strong>. \u201cAt this year\u2019s ESMO, we will present data from three clinical trials with BNT327\/PM8002, one of the key backbones for our combination treatment strategy. This bispecific antibody will be an element in multiple novel combination treatment approaches that may open up new synergistic mechanisms of action. Our mRNA platforms are another important component of our combination strategy. At ESMO, we will present clinical data that further support the proof of concept of our mRNA-based FixVac approach, which targets non-mutated tumor-associated antigens, showing early clinical activity across various indications.\u201d<\/p>\n<p align=\"justify\"><strong>Highlights of BioNTech\u2019s clinical stage programs to be presented at ESMO Congress 2024:<\/strong><\/p>\n<ul>\n<li style=\"text-align:justify;\">Updates on several Phase 2 and Phase 1\/2 clinical trials evaluating <strong>BNT327\/PM8002<\/strong> in various indications as monotherapy and in combination with chemotherapy will be presented. BNT327\/PM8002 is an investigational bispecific antibody combining PD-L1 checkpoint inhibition with VEGF-A neutralization for vascular normalization and immunostimulation in the microenvironment of the tumor. Two oral presentations and one poster will provide clinical data updates for cohorts with advanced non-small cell lung cancer (\u201cNSCLC\u201d), locally advanced\/metastatic triple-negative breast cancer (\u201cTNBC\u201d) and advanced renal cell carcinoma. BNT327\/PM8002 is being developed in collaboration with Biotheus Inc. (\u201cBiotheus\u201d).<\/li>\n<li style=\"text-align:justify;\">Preliminary data from an ongoing clinical Phase 2 trial (<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=h_H40dwmcn_9aW-_tvXfVN45EzauMFzF9UgGxizD94daDiS5tKkjztLR89GxeVBbFq-yM_8it_eAoE6odHYgDYovie4qIjO0wqT4X-neT4abxquZQtKd-kCxvAJITv1I\" rel=\"nofollow noopener\" target=\"_blank\" title=\"\"><u>NCT04534205<\/u><\/a>) evaluating <strong>BNT113<\/strong> in combination with PD-1 blockade and data from an investigator-initiated Phase 1\/2 clinical trial (<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=h_H40dwmcn_9aW-_tvXfVPBKKbk1PCKCZOiL5Q7eWz_Mwd9ZN6POLODXrplmjfpbXKq_k7ksmUZJahEdc_QzEzn6sVaBK5F8qsk0_jlXZAAHod_V5vMPlX6MSP6hO-F5\" rel=\"nofollow noopener\" target=\"_blank\" title=\"\"><u>NCT03418480<\/u><\/a>) evaluating BNT113 as monotherapy in HPV16-driven cancers will be presented. The data show immunogenicity and antitumor activity in heavily pre-treated patients in several HPV16-positive indications, including head and neck cancer, and a manageable safety profile. BNT113 is an investigational lipoplex-formulated uridine mRNA immunotherapy encoding E6 and E7 antigens of HPV16.<\/li>\n<li style=\"text-align:justify;\">Preliminary data of the randomized Phase 2 clinical trial (<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=h_H40dwmcn_9aW-_tvXfVMKhLmKMaswy6ND4awO_DG0pWe7Sx3NPVs89yjoB0YYV_5jbvL5UAIT8x3RLTOwMCDSLcBClZ6Qwn1mk1OhTlxLJRap_AinWbL_mtfQa5V1M\" rel=\"nofollow noopener\" target=\"_blank\" title=\"\"><u>NCT05446298<\/u><\/a>) with <strong>BNT316\/ONC-392 <\/strong><strong>(gotistobart),<\/strong> an investigational anti-CTLA-4 antibody, in combination with pembrolizumab in patients with platinum-resistant recurrent ovarian cancer (\u201cPROC\u201d) will be presented in a late-breaking session. BNT316\/ONC-392 is being developed in collaboration with OncoC4, Inc. (\u201cOncoC4\u201d).<\/li>\n<li style=\"text-align:justify;\">Follow-up data of activity and immune responses from the ongoing first-in-human Phase 1 clinical trial (<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=h_H40dwmcn_9aW-_tvXfVCU74x71ME-X0CCb-CtCljTLfzZLkoWrtqTCKPJ6D1khjJOeyDrRbDG5DQiEJKyNdwib7Fn_woUO9UjxjrFzgSfRa38KG1mFA2VNzilSUinN\" rel=\"nofollow noopener\" target=\"_blank\" title=\"\"><u>NCT04503278<\/u><\/a>) with <strong>BNT211<\/strong> in patients with relapsed\/refractory CLDN6+ solid tumors will be presented. BNT211 combines autologous CAR-T cells directed against the oncofetal antigen Claudin-6 (\u201cCLDN6\u201d) and an CLDN6-encoding CAR-T cell amplifying mRNA vaccine (\u201cCARVac\u201d). The data update shows signs of antitumor activity across all indications and an increased persistence of cancer-specific CAR-T cells when combined with CARVac, for example in patients with testicular and ovarian cancers. The safety profile is consistent with the previously published data of CAR-T therapies. <\/li>\n<\/ul>\n<p align=\"justify\">BioNTech has established a diversified clinical oncology pipeline including mRNA-based therapeutic cancer vaccines, targeted therapies comprising cell therapies and ADCs, and novel immunomodulators in unmet medical need solid tumor indications. These investigational treatments are currently being evaluated in more than 32 clinical trials, including eight programs in advanced Phase 2 trials and two assets in pivotal Phase 3 trials globally. BioNTech is advancing the Company\u2019s key programs into late-stage development with the aim of having ten or more potentially registrational trials in its oncology pipeline by the end of 2024.\u00a0 <\/p>\n<p align=\"justify\">The full abstracts are available on the <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=HESxcE09xjmSrI7A2OoqLvu1WacOD9T88S4FUnf_1LFArGLvW9erLDaAO8UsbGQIXSl8ECXrqxlalfghLnOL5pKQhbDh2n5nI81EJu836zg5HI0N4vkk0-YCTgd1osXc3kPBgO4JBnvs6AQ2T_wGKSO6AnRPRKxj4YHvlZMHIEI=\" rel=\"nofollow noopener\" target=\"_blank\" title=\"\"><u>ESMO Congress website<\/u><\/a>. Click <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=57yUP5Y0nEe8Tyk6s_BL2bDksKbw-216PQ5DZ7SsZ6bBSstmiJd0lSt8F1XjKEcwYmRR9w8yaBJ5RUXvn794HFA9oE1wm2MakRjTDlauLD8UAxF4gAiuyA430K5eIWMrwdLguDvfKuaYzSKsOI39HA==\" rel=\"nofollow noopener\" target=\"_blank\" title=\"\"><u>here<\/u><\/a> for further information on BioNTech\u2019s pipeline assets. <\/p>\n<p align=\"justify\"><strong><u>Full presentation details:<\/u><\/strong><\/p>\n<p align=\"justify\"><strong>Late-breaking presentation<\/strong><br \/><em>Asset<\/em>: BNT316\/ONC-392 (gotistobart)<br \/><em>Session title: <\/em>Mini oral session 1: Gynaecological cancers (ID 166)<br \/><em>Room<\/em>: Burgos Auditorium &#8211; Hall 5<br \/><em>Presentation title<\/em>: \u201cA randomized, Phase 2, dose optimization of gotistobart, a pH-sensitive anti-CTLA-4, in combination with standard dose pembrolizumab in platinum-resistant recurrent ovarian cancer: safety, efficacy and dose optimization (PRESERVE-004\/GOG-3081)\u201d<br \/><em>Presentation number:<\/em> LBA32<br \/><em>Date: <\/em>Sunday, September 15, 2024 <br \/><em>Lecture time: <\/em>09:10 AM \u2013 09:15 AM CEST<\/p>\n<p align=\"justify\"><strong>Mini oral presentations<\/strong><br \/><em>Asset<\/em>: BNT113<br \/><em>Session title: Mini oral session: <\/em>Investigational immunotherapy<br \/><em>Room<\/em>: Granada Auditorium &#8211; Hall 6<br \/><em>Presentation title<\/em>: \u201cHARE-40: A phase I\/II trial of therapeutic HPV vaccine (BNT113) in patients with HPV16 driven carcinoma\u201d<br \/><em>Presentation number:<\/em> 999MO<br \/><em>Date: <\/em>Monday, September 16, 2024 <br \/><em>Lecture time: <\/em>11:15 AM \u2013 11:20 AM CEST<\/p>\n<p align=\"justify\"><em>Asset<\/em>: BNT211<br \/><em>Session title: <\/em>Proffered paper session 2: Developmental therapeutics<br \/><em>Room<\/em>: Salamanca Auditorium &#8211; Hall 5<br \/><em>Presentation title<\/em>: \u201cUpdated results from BNT211-01 (NCT04503278), an ongoing, first-in-human, Phase 1 study evaluating safety and efficacy of CLDN6 CAR T cells and a CLDN6-encoding mRNA vaccine in patients with relapsed\/refractory CLDN6+ solid tumors\u201d<br \/><em>Presentation number:<\/em> 611O<br \/><em>Date: <\/em>Sunday, September 15, 2024 <br \/><em>Lecture time: <\/em>03:45 PM \u2013 03:55 PM CEST<\/p>\n<p align=\"justify\"><em>Asset<\/em>: BNT327\/PM8002<br \/><em>Session title: <\/em>Mini oral session: NSCLC metastatic<br \/><em>Room<\/em>: Santander Auditorium &#8211; Hall 5<br \/><em>Presentation title<\/em>: \u201cA Phase II Safety and Efficacy Study of PM8002\/BNT327 in Combination with Chemotherapy in Patients with EGFR-mutated Non-Small Cell Lung Cancer (NSCLC)\u201d<br \/><em>Presentation number:<\/em> 1255MO<br \/><em>Date: <\/em>Saturday, September 14, 2024 <br \/><em>Lecture time: <\/em>10:20 AM \u2013 10:25 AM CEST<\/p>\n<p align=\"justify\"><em>Asset<\/em>: BNT327\/PM8002<br \/><em>Session title: <\/em>Mini oral session 2: Breast cancer, metastatic<br \/><em>Room<\/em>: Barcelona Auditorium &#8211; Hall 2<br \/><em>Presentation title<\/em>: \u201cA Phase Ib\/II Study to Assess the Safety and Efficacy of PM8002\/BNT327 in Combination with Nab-Paclitaxel for First Line Treatment of Locally Advanced or Metastatic Triple-Negative Breast Cancer\u201d<br \/><em>Presentation number:<\/em> 348MO<br \/><em>Date: <\/em>Monday, September 16, 2024 <br \/><em>Lecture time: <\/em>08:35 AM \u2013 08:40 AM CEST<\/p>\n<p align=\"justify\"><strong>Posters<\/strong><br \/><em>Asset<\/em>: BNT113<br \/><em>Poster title<\/em>: &#8221; Exploratory efficacy and translational results from the safety run in of AHEAD-MERIT, a phase II trial of first line pembrolizumab plus the fixed-antigen cancer vaccine BNT113 in advanced HPV16+ HNSCC &#8220;<br \/><em>Room: <\/em>Hall 6<br \/><em>Poster number<\/em>: 877P<br \/><em>Date: <\/em>Saturday, September 14, 2024<\/p>\n<p align=\"justify\"><em>Asset<\/em>: BNT314\/GEN1059<br \/><em>Poster title<\/em>: \u201cPhase 1\/2 dose escalation\/expansion trial to evaluate safety and preliminary efficacy\u00a0of\u00a0DuoBody-EpCAMx4-1BB (BNT314\/GEN1059) alone or in combination with\u00a0an immune checkpoint inhibitor in patients with malignant solid tumors\u201d<br \/><em>Room: <\/em>Hall 6<br \/><em>Poster number<\/em>: 1072TiP<br \/><em>Date: <\/em>Saturday, September 14, 2024<\/p>\n<p align=\"justify\"><em>Asset<\/em>: BNT323\/DB-1303<br \/><em>Poster title<\/em>: \u201cDYNASTY-Breast02: A Phase 3 trial of BNT323\/DB-1303 vs Investigator&#8217;s Choice Chemotherapy\u00a0in\u00a0HER2-low, Hormone Receptor Positive, Metastatic Breast Cancer\u201d<br \/><em>Room: <\/em>Hall 6<br \/><em>Poster number<\/em>: 436TiP<br \/><em>Abstract number:<\/em> 7363<br \/><em>Date: <\/em>Monday, September 16, 2024<\/p>\n<p align=\"justify\"><em>Asset<\/em>: BNT327\/PM8002<br \/><em>Poster title<\/em>: \u201cA Phase Ib\/IIa Trial to Evaluate the Safety and Efficacy of PM8002\/ BNT327, a Bispecific Antibody Targeting PD-L1 and VEGF-A, as a Monotherapy in Patients with advanced renal cell carcinoma\u201d<br \/><em>Room: <\/em>Hall 6<br \/><em>Poster number<\/em>: 1692P<br \/><em>Date: <\/em>Sunday, September 15, 2024<\/p>\n<p align=\"justify\"><strong>About BioNTech<\/strong><br \/>Biopharmaceutical New Technologies (BioNTech) is a global next generation immunotherapy company pioneering novel therapies for cancer and other serious diseases. BioNTech exploits a wide array of computational discovery and therapeutic drug platforms for the rapid development of novel biopharmaceuticals. Its broad portfolio of oncology product candidates includes individualized and off-the-shelf mRNA-based therapies, innovative chimeric antigen receptor (CAR) T cells, several protein-based therapeutics, including bispecific immune checkpoint modulators, targeted cancer antibodies and antibody-drug conjugate (ADC) therapeutics, as well as small molecules. Based on its deep expertise in mRNA vaccine development and in-house manufacturing capabilities, BioNTech and its collaborators are developing multiple mRNA vaccine candidates for a range of infectious diseases alongside its diverse oncology pipeline. BioNTech has established a broad set of relationships with multiple global and specialized pharmaceutical collaborators, including Biotheus, DualityBio, Fosun Pharma, Genentech, a member of the Roche Group, Genevant, Genmab, MediLink, OncoC4, Pfizer and Regeneron. <\/p>\n<p align=\"justify\">For more information, please visit <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=mxWKIbrOL2VXl-am5o3SUtbfCv4gDIp-TgDnfAxGsiJ04GyrYf4HCN2se486xQ3Jbn2z9VmKdywSW7qps0AgAE3fcCI4Qae6cfkJoh-_N1gxKQsSQaS8fQKF154jnGPe\" rel=\"nofollow noopener\" target=\"_blank\" title=\"\"><u>www.BioNTech.com<\/u><\/a>.<\/p>\n<p align=\"justify\"><strong>BioNTech Forward-Looking Statements<\/strong><br \/>This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, including, but not limited to, statements concerning: the initiation, timing, progress and results of BioNTech\u2019s research and development programs in oncology, including the targeted timing and number of additional potentially registrational trials; BioNTech\u2019s and its collaborators\u2019 current and future preclinical studies and clinical trials in oncology, including the investigational lipoplex-formulated uridine mRNA immunotherapy BNT113, the investigational bispecific antibodies BNT327\/PM8002 and BNT314\/GEN1059, the investigational anti-CTLA-4 antibody BNT316\/ONC-392 (gotistobart) in combination with pembrolizumab, the investigational CAR-T cell therapy BNT211, and the investigational ADC therapy BNT323\/DB-1303; the nature and characterization of and timing for release of clinical data across BioNTech\u2019s platforms, which is subject to peer review, regulatory review and market interpretation; the planned next steps in BioNTech\u2019s pipeline programs, including, but not limited to, statements regarding timing or plans for initiation or enrollment of clinical trials, or submission for and receipt of product approvals and potential commercialization with respect to BioNTech\u2019s product candidates; the ability of BioNTech\u2019s mRNA technology to demonstrate clinical efficacy outside of BioNTech\u2019s infectious disease platform; and the potential safety and efficacy of BioNTech\u2019s product candidates. In some cases, forward-looking statements can be identified by terminology such as \u201cwill,\u201d \u201cmay,\u201d \u201cshould,\u201d \u201cexpects,\u201d \u201cintends,\u201d \u201cplans,\u201d \u201caims,\u201d \u201canticipates,\u201d \u201cbelieves,\u201d \u201cestimates,\u201d \u201cpredicts,\u201d \u201cpotential,\u201d \u201ccontinue,\u201d or the negative of these terms or other comparable terminology, although not all forward-looking statements contain these words.<\/p>\n<p align=\"justify\">The forward-looking statements in this press release are based on BioNTech\u2019s current expectations and beliefs of future events, and are neither promises nor guarantees. You should not place undue reliance on these forward-looking statements because they involve known and unknown risks, uncertainties, and other factors, many of which are beyond BioNTech\u2019s control and which could cause actual results to differ materially and adversely from those expressed or implied by these forward-looking statements. These risks and uncertainties include, but are not limited to: the uncertainties inherent in research and development, including the ability to meet anticipated clinical endpoints, commencement and\/or completion dates for clinical trials, regulatory submission dates, regulatory approval dates and\/or launch dates, as well as risks associated with preclinical and clinical data, including the data discussed in this release, and including the possibility of unfavorable new preclinical, clinical or safety data and further analyses of existing preclinical, clinical or safety data; the nature of clinical data, which is subject to ongoing peer review, regulatory review and market interpretation; the ability to produce comparable clinical results in future clinical trials; the timing of and BioNTech\u2019s ability to obtain and maintain regulatory approval for its product candidates; discussions with regulatory agencies regarding timing and requirements for additional clinical trials; BioNTech\u2019s and its counterparties\u2019 ability to manage and source necessary energy resources; BioNTech\u2019s ability to identify research opportunities and discover and develop investigational medicines; the ability and willingness of BioNTech\u2019s third-party collaborators to continue research and development activities relating to BioNTech\u2019s development candidates and investigational medicines; unforeseen safety issues and potential claims that are alleged to arise from the use of products and product candidates developed or manufactured by BioNTech; BioNTech\u2019s and its collaborators\u2019 ability to commercialize and market, if approved, its product candidates; BioNTech\u2019s ability to manage its development and expansion; regulatory developments in the United States and other countries; BioNTech\u2019s ability to effectively scale its production capabilities and manufacture its products and product candidates; risks relating to the global financial system and markets; and other factors not known to BioNTech at this time.<\/p>\n<p align=\"justify\">You should review the risks and uncertainties described under the heading \u201cRisk Factors\u201d in BioNTech&#8217;s Report on Form 6-K for the period ended June 30, 2024, and in subsequent filings made by BioNTech with the SEC, which are available on the SEC\u2019s website at <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=mxWKIbrOL2VXl-am5o3SUgKEcDeDftK-EeupGApXHC4wFH4gmiC0-WWHFhkLD6Pbu1lm0uAnMQAaJ5G3sde6pw==\" rel=\"nofollow noopener\" target=\"_blank\" title=\"\"><u>www.sec.gov<\/u><\/a>. These forward-looking statements speak only as of the date hereof. Except as required by law, BioNTech disclaims any intention or responsibility for updating or revising any forward-looking statements contained in this press release in the event of new information, future developments or otherwise.<\/p>\n<p align=\"justify\"><strong>CONTACTS<\/strong><br \/><strong><br \/>Media Relations<\/strong><br \/>Jasmina Alatovic<br \/>+49 (0)6131 9084 1513<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=gOTqR-GywNyZDDVl__7fjlNzPhDkWGlaCWAdupsneuB4XHPfcvBIovcQkZUh2d34hq2ynyGTzCSL5wE93_et_1FPjI3uZJes2G3cYA0XGQs=\" rel=\"nofollow noopener\" target=\"_blank\" title=\"\"><u>Media@biontech.de<\/u><\/a><\/p>\n<p align=\"justify\"><strong>Investor Relations<\/strong><br \/>Victoria Meissner, M.D.<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=Idr5fopLMgmZvZ-fQNCWVqO0dKQTMF5N0PGzgyoRpTdeyxoY_DcKKx-QrmAhfBt2I_DYf2565tINhrf4ZG-5QMw2sgHBGPBeYkXkZGuPkz4=\" rel=\"nofollow noopener\" target=\"_blank\" title=\"\"><u>Investors@biontech.de<\/u><\/a><\/p>\n<p>\n            <\/div>\n","protected":false},"excerpt":{"rendered":"<p>MAINZ, Germany, September 05, 2024 \u2013 BioNTech SE (Nasdaq: BNTX, \u201cBioNTech\u201d or \u201cthe Company\u201d) will present clinical trial data for selected assets from its multi-platform oncology pipeline at the European Society for Molecular Oncology (\u201cESMO\u201d) Congress 2024 in Barcelona, Spain from September 13-17, 2024. The oral and poster presentations will feature programs across BioNTech\u2019s clinical [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":84407,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"fifu_image_url":"https:\/\/ml-eu.globenewswire.com\/Resource\/Download\/b9e2e00e-f790-4d54-a01f-4c85716b01bd","fifu_image_alt":"","footnotes":""},"categories":[208],"tags":[],"class_list":["post-84406","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-globenewswire"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/pakistaninewspaperlist.com\/news\/wp-json\/wp\/v2\/posts\/84406","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pakistaninewspaperlist.com\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pakistaninewspaperlist.com\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pakistaninewspaperlist.com\/news\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pakistaninewspaperlist.com\/news\/wp-json\/wp\/v2\/comments?post=84406"}],"version-history":[{"count":0,"href":"https:\/\/pakistaninewspaperlist.com\/news\/wp-json\/wp\/v2\/posts\/84406\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pakistaninewspaperlist.com\/news\/wp-json\/wp\/v2\/media\/84407"}],"wp:attachment":[{"href":"https:\/\/pakistaninewspaperlist.com\/news\/wp-json\/wp\/v2\/media?parent=84406"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pakistaninewspaperlist.com\/news\/wp-json\/wp\/v2\/categories?post=84406"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pakistaninewspaperlist.com\/news\/wp-json\/wp\/v2\/tags?post=84406"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}